Lower Inflammation Load
Helps reduce circulating factors that can contribute to chronic low-grade inflammation.
Scottsdale, AZ • Therapeutic Plasma Exchange (TPE)
Deep Blood Detox for Microplastics, Mold & Heavy Metals
An advanced plasma exchange procedure designed to remove unwanted circulating toxins and inflammatory factors—supporting cleaner blood, stronger resilience, and a healthier internal environment.
Provider
Dr. Keith Smigiel
FNP-C, DC, FIAMA • Regenerative Medicine & Pain Management
Clinic
ReGen Pain & Wellness
Scottsdale, Arizona • Natural Heart Doctor Building www.regenpainandwellness.com
What This Treatment Targets
A Cleaner Blood Environment Starts By Removing What Shouldn't Be There
Therapeutic Plasma Exchange(TPE) is designed to reduce unwanted circulating factors in the plasma – supporting detox, immune balance, and overall resilience.
Microplastic
Tiny plastic particles that can enter the body through food, water, and air—and circulate through the bloodstream.
- ✓ Supports reducing unwanted circulating particles
- ✓ Helps promote a cleaner internal environment
- ✓ Designed to lower overall inflammatory load
Mold / Mycotoxins
Environmental toxins produced by mold that may contribute to inflammation, fatigue, and brain fog in sensitive individuals.
- ✓ Helps reduce mold-related circulating toxins
- ✓ Supports detox pathways and immune balance
- ✓ May help improve clarity, energy, and resilience
Produced by heavy metals Heavy Metals
Environmental toxins produced by mold that may contribute to inflammation, fatigue, and brain fog in sensitive individuals.
- ✓ Supports reducing unwanted heavy metal burden
- ✓ Helps promote neurological and immune stability
- ✓ Complements long-term longevity strategies
Want to know if TPE is a good fit for your goals?
Talk with out team for a personalized consult.
How It Works
How Therapeutic Plasma Exchange Cleans Your Blood
A medically supervised process designed to remove unwanted circulating toxins while preserving the vital components your body needs.
Blood Is Gently Drawn
Blood is drawn through an IV in a controlled clinical setting under professional medical supervision.
Plasma Is Separated
The plasma – where toxins like microplastics, mold toxins, and heavy metals circulate – is separated from the blood cells.
Clean Blood is Returned
Blood cells are returned to the body with albumin replacement, supporting a cleaner internel environment.
Duration: 2-4 Hours
Settings: Outpatient
Care: Medically Supervised
Key Benefits
What You May Notice After Cleaner Blood
By reducing unwanted circulating toxins and inflammatory factors, TPE supports a healthier internal environment— helping your body recover, perform, and stay resilient.
Microplastics Focus
Mold / Mycotoxins
Heavy Metals
6
core benefits
2–4 hrs
typical session
Clearer Mind
Supports focus and clarity by improving the overall quality of the internal environment.
Energy & Recovery Support
Many clients pursue TPE to support stamina, recovery, and day-to-day performance.
Immune Resilience
Supports immune balance by reducing plasma burden from unwanted circulating factors.
Circulation Support
A cleaner blood environment can support healthy flow, delivery, and overall vitality.
Whole-Body Detox Support
Designed to target blood-level toxins like microplastics, mold toxins, and heavy metals.
Evidence & Media
Why People Are Exploring Blood Cleansing form Modern Toxins
Public interest in “blood cleansing” has grown – especially around environment burdens like microplastics, mold toxins, and heavy metals. Beloa are two helpful refrences: a media mention and a sample-style lab snapshot for context.
Trend awareness + public concersation
A recent article highlighted how some longevity-focused individuals are spending on “blood cleansing approaches to reduce unwanted circulating toxins. Use this as a conversation starter-not as a guarantee of results.
Note: Media mentions are information only. Individual results vary.
Testing Snapshot Example
Expected Outcomes
What You May Notice As Your Internal Environment Gets Cleaner
While every person is diffrent, many clients pursue Therapeutic Plasma Exchange to support clearer thinking, better day-to-day energy, and a lower overall toxin and inflammation burden-especially from microplastics, mold toxins, and heavy metals.
Clear Mind & Focus
Reducing unwanted circulating factors may help support mental clarity, less “brain fog”, and sharper day-to-day decision making.
More Steady Energy
A cleaner internal environment can support better recovery, more balanced stamina, and more “good days” in a row.
Inflammation Load Support
By targeting blood-level toxins and inflammatory madiators, TPE may contribute to a lower overall inflammatory burden over time.
FAQ
Common Questions About Therapeutic Plasma Exchange
Here are answers to the questions people most often ask about using Therapeutic Plasma Exchange(TPE) to help reduce blood-level toxins like microplastics, mold-related toxins, and heavy metals. This information is general and does not replace a one-on-one medical consultation.
Is Therapeutic Plasma Exchange safe?
TPE is a well-established medical procedure that has been used for decades in hospitals and specialty clinics. Like any medical treatment, it has potential risks and side effects, which your clinician will review with you based on your health history, medications, and goals.
How long does a typical session take?
Most TPE sessions last around 2–4 hours. You’ll be seated or reclined while your blood is gently circulated through the machine, your plasma is exchanged, and your blood cells are returned to your body.
Will I feel a difference right away?
Everyone is different. Some people notice changes in clarity, energy, or overall wellbeing within days or weeks, while others experience more gradual shifts. TPE is usually part of a broader plan that includes lifestyle, sleep, nutrition, and other therapies.
Does TPE really help with microplastics, mold, and heavy metals?
TPE removes and replaces plasma, where many circulating toxins and inflammatory factors travel.
The goal is to help reduce overall toxin burden in the blood—supporting protocols that target microplastics, mold-related toxins, and certain heavy metals under medical supervision.
How many sessions might I need?
The number of sessions depends on your goals, lab findings, and overall health. Some people complete a short series, while others follow a longer protocol. Your provider will recommend a plan after reviewing your evaluation and test results
How do I know if I’m a good candidate?
The best next step is a consultation. Your symptoms, exposure history (such as mold or environmental toxins), lab work, and overall health are reviewed to determine whether TPE is appropriate—and to discuss alternatives
if it’s not the right fit.
Still have questions? A brief consultation can help you understand whether TPE fits your health and longevity goals.
Scottsdale, AZ • Therapeutic Plasma Exchange (TPE)
Ready to Talk About Blood Detox & Toxin Burden?
If microplastics, mold exposure, or heavy metals are on your mind, a focused consult can help you understand whether Therapeutic Plasma Exchange fits into your health and longevity plan-and what a personalized protocoll could look for you.
PROVIDER
Dr. Keith Smigiel, FNP-C, DC, FIAMA
Regenerative Medicine & Pain Management
LOCATION
ReGen Pain & Wellness
Inside Natural Heart Doctor • Scottsdale, AZ
VISIT TYPE
Outpatient • Appointment Only
No walk-ins • Limited availabilit